homocysteine相关论文
Correlation between plasma cysteine C, homocysteine, high sensitivity C-reactive protein, and D-dime
Background and objective: Cerebral infarction is a common disease with high mortality and morbidity rates. Its occurrenc......
目的:探讨同型半胱氨酸(HCY)联合纤维蛋白原(FIB)、超敏C反应蛋白(hsCRP)预测急性胸痛患者心脏事件的价值.方法:选择2018年2月至20......
Status of hyperhomocysteinemia in China:results from the China Stroke High-risk Population Screening
A nationwide survey was conducted from October 2018 to September 2019 to assess the prevalence of hyperhomocysteinemia(H......
A GLP-1 analog lowers ER stress and enhances protein folding to ameliorate homocysteine-induced endo
Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular diseases and increases mortality in type 2 ......
Genetic association of plasma homocysteine levels with gastric cancer risk:a two-sample Mendelian ra
Objective In China,gastric cancer(GC)is the second common incident cancer and the second leading cause of cancer death w......
Homocysteine induces C-reactive protein expression in rat smooth muscle cells via NMDAr-ROS-MAPK sig
Aim: As an inflammatory marker, C-reactive protein (CRP) plays a direct role in atherosclerotic process.Homocysteine (Hc......
A regulatory circuit of miR-143 and DNMT3a mediated vascular smooth muscle cells proliferation induc
Accumulating evidence has strongly suggested that homocysteine (Hcy) is an independent risk factor of atherosclerosis (A......
Endoplasmic reticulum oxidoreductin 1α mediates hepatic endoplasmic reticulum stress in homocysteine
Endoplasmic reticulum (ER) stress is emerging as an important modulator of different pathological process and as a mecha......
Association study between aberrant DNA methylation in promoter of DDAH2 gene and dysfunction of EPCs
Aim: it has been demonstrated that circulating EPCs may be a biomarker for vascular function and cardiovascular risk in ......
A meta-analysis of the association between homocysteine, vitamin B12, folate, and bone mineral densi
Aim: Previous studies have reported inconsistent findings regarding the associations between homocysteine (Hcy), vitamin......
Correlation analysis about serum homocysteine and high sensitivity C reactive protein and coronary h
Objective To investigate the meaning of serum homocysteine (Hcy) and high sensitive C reactive protein (hs CRP) associat......
Homocysteine lowering by folic acid supplement reversed hyperhomocysteinemia aggravated angⅡ-induced
Abdominal aortic aneurysm (AAA), defined as a 50% increase in external diameter of the abdominal aorta, is one of the le......
CTLA4-IGG ameliorates homocysteine-accelerated atherosclerosis by inhibiting T-cell overactivation i
Objectives Hyperhomocysteinemia (HHcy) accelerates atherosclerosis in apoE-/-mice by promoting T-cell activation, prolif......
Background & Aims: Aberrant DNA methylation in gene promoter plays a major role in tumorigenesis.Previous studies have s......
Irritable bowel syndrome (IBS),a common functional gastrointestinal disorder,is characterized by altered bowel evacuatio......
Homocysteine increased ER-mitochondrial coupling with promoting mitochondrial respiration and T cell
Homocysteine (Hcy) is a sulfur-containing non-constitutive amino acid derived from the essential amino acid methionine.N......
Increased concentrations of homocysteine and decreased status of folate and vitamin B12 in women wit
Objective:To analyze the associations between early concentrations of Hcy, folate and VB12 and subsequent events of adve......
Hyperhomocysteinemia induced by methionine supplementation independently cause and promotes atherosc
Background Hyperhomcysteine was found to be an independent risk factor of coronary heart disease.But whether it really i......
H2S protects endothelium cell against Hcy-induced apoptosis and promotes cystathionine-γ-lyase expre
Aim: To investigate the role of the H2S effect in atherosclerosis (AS).Methods: The HUVECs were divided into the followi......
A natural squamosamide derivative FLZ inhibits homocysteine-induced rat brain microvascular endothel
OBJECTIVE Compound FLZ is a novel synthetic squamosamide cyclic analogue with several phenolichydroxy groups.Previous re......
Hyperhomocysteinemia promotes insulin resistance by inducing endoplasmic reticulum stress in adipose
Aims: Type 2 diabetes is a chronic inflammatory metabolic disease, the key point being insulin resistance.Endoplasmic re......
Nitration-mediated deficiency of cystathionine β-synthase activity in diet-induced hyperhomocysteine
Deficiency of cystathionine β-synthase (CBS) activity is the most common cause of hyperhomocysteinemia (HHcy),and incre......
An elevated plasma homocysteine level (hyperhomocysteinemia,HHcy) has been reported to be associated with neurode-genera......
Aim: To explore the relationship between plasma total homocysteine concentration and diabetic neuropathy in Chinese pati......
Homocysteine mediated maternal separation stress-induced irritable bowel syndrome by increasing inte
Background: Irritable bowel syndrome(IBS)is considered to be a functional gastrointestinal disorder characterized by chr......
Correlation of the elevated plasma homocysteine with carotid artery plaques in acute cerebral infarc
Background: To investigate the relationship between the level of plasma homocysteine (Hcy) and carotid artery plaques in......
The ratio of S-adenosylmethionine to S-adenosylhomocysteine is a more sensitive indicator of atheros
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The effects of different doses of atorvastatin calcium on the levels of homocysteine and uric acid i
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The relationship between the homocysteine levels and SYNTAX score of coronary artery lesion in the p
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Protective effects and possible mechanisms of anti-neuronal apoptosis of Xanthoceraside on PC12 cell
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目的 通心络胶囊是根据络病理论而研制的复方制剂,通心络胶囊是由人参、水蛭、全蝎、土鳖虫、蜈蚣、蝉蜕、赤芍、冰片等中药组成的......
目的 动脉粥样硬化(AS)是心脑血管疾病发生发展的基础,血管内皮细胞功能异常是AS的早期标志.现已证明血管内皮细胞产生的一氧化氮(......
对同型半胱氨酸的太赫兹特征吸收光谱进行分析。首先使用密度泛函理论分析同型半胱氨酸分子的振动和转动模式,确保其理论吸收峰位......
同型半胱氨酸是一种含硫氨基酸, 为蛋氨酸和半胱氨酸代谢过程中产生的重要中间产物, 它在人体血液或尿液中浓度含量过高时会大幅增......
The radiation protector homocysteine thiolactone induces cell proliferation but has no protective ef
Objectives Homocysteine thiolactone (HCTL) is a normal metabolite of amino acid metabolism,and has been proved as a potenti......
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Biomarkers enhance the long-term predictive ability of the KAMIR risk score in Chinese patients with
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The relationship between MTHFR gene polymorphisms, plasma homocysteine levels and diabetic retinopat
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Diet-induced hyperhomocysteinemia exacerbates vascular reverse remodeling of balloon-injured arterie
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Localization of cystathionine β synthase in mice ovaries and its expression profile during follicula
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Potential biomarkers predicting risk of pulmonary hypertension in congenital heart disease: the role
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β-淀粉样蛋白(amyloid-β pprotein,Aβ)不但在阿尔茨海默病(Alzheimer disease,AD)中起关键作用,而且还与脑小血管病有关。血清总同型......
目的探讨尿液早期肾功能损伤标志物与血清同型半胱氨酸(Hcy)升高的相关性。方法对2019年1月至2020年5月于北京大学第三医院体检中心......